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Lipitor - Atorvastatin

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Generic Name : Atorvastatin
Brand Names : Lipitor

What is Lipitor or Atorvastatin?

Lipitor (Atorvastatin) to a group of drugs known as statins, used along with a proper diet to help lower "bad" cholesterol and fats (e.g., LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It works by reducing the amount of cholesterol made by the liver. In general, atorvastatin is prescribed after non-drug treatments have not been fully successful at lowering cholesterol (e.g., diet change, increase in exercise, weight loss if overweight). Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.

Indications

Lipitor (Atorvastatin) is indicated to help lower "bad" cholesterol and fats (e.g., LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood

Dosage

Dosage is based on the medical condition of the patient and response to therapy and use of certain interacting medicines. Many of the drugs listed in the Drug Interactions section may increase the chances of muscle problems when used with atorvastatin. The doctor should be consulted properly.

The patient should avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless the doctor instructs. Grapefruit juice can increase the amount of certain medications in the bloodstream. The patient should take this medication regularly in order to get the most benefit from it. It may take up to 4 weeks before the patient gets the full benefit of this drug. It is important to continue taking this medication even if the patient is feeling well. Most people with high cholesterol or triglycerides do not feel sick.

Side Effects

The various reported side effects of the drug are:

Diarrhea or stomach/abdominal, muscle pain/tenderness/weakness (especially with fever or unusual tiredness), change in the amount of urine, yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting. This drug may infrequently cause muscle problems (which can rarely lead to a very serious condition called rhabdomyolysis).

Drug Interactions

Before using this medication, consultation should be done with the doctor or pharmacist of all prescription and nonprescription/herbal products the patient is using, especially of: aliskiren, hormonal birth control (e.g., pills, patch, ring), clopidogrel, daptomycin, digoxin, drugs affecting liver enzymes that remove atorvastatin from the body (such as azole antifungals including itraconazole/ketoconazole, certain macrolide antibiotics including erythromycin/clarithromycin/troleandomycin, HIV protease inhibitors including indinavir/ritonavir, amiodarone, cyclosporine, diltiazem, efavirenz, nefazodone, rifampin, St. John's wort, carbamazepine).

Overdose

If overdose is suspected, the patient should contact the local poison control center or emergency room immediately. Laboratory and/or medical tests (e.g., blood cholesterol/triglyceride levels, liver function tests) should be performed periodically to monitor the progress or check for side effects.

For best results, this medication should be used along with exercise, a low-cholesterol/low-fat diet, and a weight loss program if the patient is overweight. To help reduce the risk of heart attacks and strokes, the patient should check the blood pressure regularly, and should seek medical treatment if blood pressure is high, and should stop smoking.

Contraindications

The patient should tell the doctor his medical history, especially of: history of liver disease, kidney disease, alcohol use/abuse

Precautions


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