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BONIVA - Ibandronate sodium

Generic Name : Ibandronate sodium
Brand Names : BONIVA

What is Ibandronate sodium or Boniva?

Boniva (Ibandronate Sodium) is a nitrogen-containing bisphosphonate that inhibits osteoclast-mediated bone resorption. Boniva is used for preventing and treating osteoporosis (weak bones) in women past menopause. Boniva (Ibandronate Sodium) alters the cycle of bone formation and breakdown in the body. Ibandronate slows bone loss while increasing bone mass, which may prevent bone fractures. This medicine may also be used for other conditions as determined by your doctor.


Ibandronate sodium or Boniva is indicated for the treatment and prevention of osteoporosis in postmenopausal women.


The recommended dose of Ibandronate sodium or Boniva for treatment of postmenopausal osteoporosis is one 2.5-mg tablet taken once daily or one 150-mg tablet taken once monthly on the same date each month. After taking an Ibandronate sodium or Boniva tablet, carefully follow these instructions:

Side Effects

Get emergency medical attention if you have any of these signs of an allergic reaction after taking Ibandronate sodium or Boniva: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using ibandronate and call your doctor at once if you have any serious side effects like chest pain; difficulty or pain when swallowing; pain or burning under the ribs or in the back; new or worsening heartburn; severe joint, bone, or muscle pain; or jaw pain, numbness, or swelling. Other less serious side effects are more likely to occur. Continue using ibandronate and talk with your doctor if you have any of these less serious side effects like redness or swelling of your eyes; diarrhea; flu symptoms; redness or swelling where the medicine was injected; nausea or upset stomach; or pain in your arms or legs. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Drug Interactions

Antacids, supplements, or medicines that contain aluminum, magnesium, iron or other minerals can interfere with how your body absorbs Ibandronate sodium or Boniva. If you use these medicines, do not that take them for at least 60 minutes after taking an Ibandronate sodium or Boniva tablet.

Before using ibandronate, you must tell your doctor if you also use aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) like celecoxib (Celebrex), diclofenac (Voltaren), diflunisal (Dolobid), ibuprofen (Motrin, Advil), indomethacin, ketoprofen (Orudis), ketorolac (Toradol), naproxen (Aleve, Naprosyn), piroxicam (Feldene), or any other. Inform your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


No specific information is available on the treatment of overdosage with Ibandronate sodium or Boniva. However, based on knowledge of this class of compounds, oral overdosage may result in hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, dyspepsia, esophagitis, gastritis, or ulcer. Seek medical help if you think you have taken overdose of Ibandronate sodium or Boniva.


Contraindicated if known hypersensitivity to BONIVA or to any of its excipients, uncorrected hypocalcemia, and inability to stand or sit upright for at least 60 minutes.


Do not take an Ibandronate sodium or Boniva tablet if you cannot sit upright or stand for at least one full hour. Ibandronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 60 minutes after taking Ibandronate sodium or Boniva.

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