Crestor® or Rosuvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. It works by reducing levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Rosuvastatin or Crestor is an enzyme blocker which is also known as a "statin." This drug is used along with a proper diet to help lower fats (triglycerides) and cholesterol in the blood. Rosuvastatin or Crestor is generally prescribed after non-drug treatment options have not been fully successful at lowering cholesterol (e.g., diet change, increase in exercise, weight loss if overweight). It is important to reduce cholesterol and triglycerides to help prevent strokes and heart attacks.
Rosuvastatin or Crestor is taken orally, usually once daily with or without food, or as directed by your doctor. Your doctor will determine the dosage of Rosuvastatin or Crestor based on your medical condition, response to therapy, and use of certain interacting medicines.
Constipation and sore throat are the common side effects of Rosuvastatin or Crestor. If these conditions persists, then contact your doctor. Seek immediate medical attention if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; joint pain; muscle pain, tenderness, or weakness (with or without fever or fatigue); pale stools; severe or persistent headache; stomach pain; swelling of the hands, ankles, or feet; yellowing of the eyes or skin.
Some medicines may interact with the usage of Rosuvastatin or Crestor. Tell your doctor about all the medicines you are taking especially any of these: Fibrates (eg, gemfibrozil, clofibrate), immunosuppressants (eg, cyclosporine), lopinavir/ritonavir, or niacin because they may increase the risk of muscle or kidney problems
Anticoagulants (eg, warfarin), cimetidine, ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Rosuvastatin
If overdose is suspected contact your doctor or seek emergency medical attention.
Rosuvastatin or Crestor is contraindicated to patients with a known hypersensitivity to any component of this product, patients with active liver disease, women who are pregnant or may become pregnant and nursing mothers.
Rosuvastatin or Crestor may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Rosuvastatin or Crestor with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Drinking alcohol daily or in large amounts may increase the risk of liver problems with Crestor. You must follow the diet and exercise program given to you by your health care provider. You should also tell your doctor or dentist that you take Crestor before you receive any medical or dental care, emergency care, or surgery. Women who may become pregnant should use effective birth control while taking Crestor.
Do not take more than the recommended dose of Rosuvastatin or Crestor in any case without consulting with your doctor. Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort. Do not use Rosuvastatin or Crestor if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Crestor is found in breast milk. Do not breast-feed while taking Crestor .